If the two typical layouts are not suited for a designer app, a custom layout can be created.
Since panes are the primary component of FOLIO layout, they are mandatory.
If there are related apps in FOLIO, a similar layout shall be used for consistency and ease of use.
If there are no related apps, designers are free to come up with their own layout. To help them do so, below are the 6 FOLIO screen views: